A retrospective study of 253 patients suggests that immune and proliferative features of the tumour influence prognosis in opposite ways in stage I triple-negative breast cancer....
A systematic review of 13 studies suggests that magnetic resonance imaging performed in the supine position is linked to fewer positive margins in breast-conserving surgery, though the evidence remain...
In 60 patients with triple-negative breast cancer treated with neoadjuvant pembrolizumab plus chemotherapy, a low neutrophil-to-lymphocyte ratio was independently associated with a higher pathological...
In HER2-positive patients with oestrogen-receptor expression of 50% or more, pathological complete response to neoadjuvant therapy is markedly lower and resistance to antibody-drug conjugates becomes ...
A multimodal framework based on dynamic contrast-enhanced MRI classifies complete or partial response of a breast tumor to neoadjuvant chemotherapy with accuracy above 90%....
A new DNA methylation model estimates breast tissue age with a mean error of three years and finds that breast tumors do not generally show accelerated epigenetic aging....
A new computational framework based on persistent homology extracts cancer-associated gene signatures that are sharper and more biologically coherent than conventional gene-selection methods....
A review of 65 studies finds AI adds most value in imaging and non-linear prediction, while conventional regression is still preferred on structured data....
Across three independent cohorts, low PGR expression is linked to higher genomic risk and poorer prognosis, but the study does not assess treatment response....
A study in 477 patients confirms that more than 20% tumor-infiltrating lymphocytes predicts better chemotherapy response, and that their form adds information....
A Spanish study of 759 breast cancer patients finds no consistent association between following cancer prevention recommendations and mammographic density....
A retrospective analysis at Hospital 12 de Octubre shows excellent outcomes in intermediate-risk PAM50 patients, yet relapses that call for refining risk stratification....