A retrospective study of 253 patients suggests that immune and proliferative features of the tumour influence prognosis in opposite ways in stage I triple-negative breast cancer....
A simulation model estimates that incorporating modern anti-HER2 therapies into Brazil's public system would cut deaths from stage II-III HER2-positive breast cancer by up to a third....
A systematic review of 13 studies suggests that magnetic resonance imaging performed in the supine position is linked to fewer positive margins in breast-conserving surgery, though the evidence remain...
A prospective cohort of 718 patients with early breast cancer supports an ultra-hypofractionated five-fraction course of post-surgical radiotherapy, with low toxicity and excellent short-term tumour c...
In 60 patients with triple-negative breast cancer treated with neoadjuvant pembrolizumab plus chemotherapy, a low neutrophil-to-lymphocyte ratio was independently associated with a higher pathological...
In HER2-positive patients with oestrogen-receptor expression of 50% or more, pathological complete response to neoadjuvant therapy is markedly lower and resistance to antibody-drug conjugates becomes ...
A review describes how gut microbiota dysbiosis and obesity combine to favour the onset and recurrence of breast cancer, and explores interventions targeting this axis....
A review examines initiatives to de-escalate neoadjuvant treatment in HER2-positive breast cancer, aiming to reduce overtreatment without losing efficacy, with support from biomarkers and imaging....
A multimodal framework based on dynamic contrast-enhanced MRI classifies complete or partial response of a breast tumor to neoadjuvant chemotherapy with accuracy above 90%....
A study of 943 patients treated with comprehensive nodal irradiation finds that living in food-insecure areas is associated with markedly lower overall survival, despite similar cancer treatments....
A meta-analysis of 15 randomized trials links this deep-tissue massage technique to reduced arm swelling, though confidence in the evidence is limited by study bias....
A new DNA methylation model estimates breast tissue age with a mean error of three years and finds that breast tumors do not generally show accelerated epigenetic aging....